Hou Zhan-peng
2009
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Journal
Journal of tianjin University of Technology
Abstract
2-nitro-4-methoxyaniline,which is an impotant intermediate of omeprazole,has been synthesized by a series reaction,such as acetylation,nitration and reduction from 4-methoxyaniline.The product yield is 71%,superior to the yield 65% in literature.A good synthesis yield has been obtained and the method could benefit for industry.