Zhou Youjun
2010
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Journal
Chinese Journal of Pharmaceuticals
Abstract
2-(Phenylthio)ethanamine,the intermediate of Bcl-2 inhibitor ABT-263 was prepared from 2-phenylthio ethyl bromide by Gabriel reaction.The results showed that 4-nitrophthalimide was better than phthalimide as the synthon with an overall yield of about 61%.