B. D. Credico, G. Reginato, Luca Gonsalvi
Jan 7, 2011
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0
Influential Citations
23
Citations
Journal
Tetrahedron
Abstract
Abstract The synthesis of new 4-carboxy oxazoles, thiazoles and thiazolidines by condensation of serine or cysteine with aldehydes or acids is described. Due to the optimization of a mild and selective procedure, which takes advantage of the positive effect of microwave irradiation on the MnO2 mediated oxidation step, the 2-substituted-4-carboxy derivatives can be obtained in multi-gram scale. Examples of coordination chemistry to Ni(II) and Co(II) are described.