Li Ming-zhu
2010
Citations
0
Influential Citations
0
Citations
Quality indicators
Journal
Journal of Medical Science Yanbian University
Abstract
OBJECTIVE To synthesize the compounds of 2-substituted ethyl 2-[1-(pyridine-2-yl)ethoxy] acetate and study its effects for ability of memory in mice.METHODSThe compounds of 2-substituted ethyl 2-[1-(pyridine-2-yl)ethoxy] acetate(5~7) were prepared by using 2-ethylpyridine,through Whol-Ziegler reaction,Williamson reaction and esterification reaction,and its effects for ability of memory in mice were studied by swimming maze test.RESULTSThe 2-morpholinoethyl 2-(1-(pyridin-2-yl)ethoxy) acetate(5) has the effect of improving the ability of memory in mice.