J. Haner, Kelsey Jack, Jaipal R. Nagireddy
Mar 1, 2011
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0
Influential Citations
6
Citations
Journal
Synthesis
Abstract
The synthesis of 2-substituted furans via palladium- and iron-catalyzed coupling utilizing 2-bromofuran is described. Whereas palladium-catalyzed Suzuki coupling effectively provided the corresponding aryl furans, little or no product was obtained by palladium-catalyzed coupling with various alkyl nucleophiles. Iron-catalyzed coupling proved effective for the synthesis of primary and secondary alkyl furans in modest yields and aryl furans in low yields.