Carson W. Reed, C. Lindsley
Oct 3, 2019
Citations
0
Influential Citations
1
Citations
Journal
Tetrahedron Letters
Abstract
Abstract In the course of our drug discovery programs, we had need to access chiral, 2-substituted thiomorpholines and their oxidized congeners, thiomorpholine 1,1-dioxides. Here, we disclose a high-yielding, general protocol for the enantioselective synthesis of C2-functionalized thiomorpholines and thiomorpholine 1,1-dioxides.