R. Pews
1990
Citations
0
Influential Citations
11
Citations
Journal
Heterocycles
Abstract
The hydrolysis of 2-t-butyl-5-halopyrimidine (halogen=bromine or chlorine) with sodium methoxide in methanol yields 2-t-butyl-5-hydroxypyrimidine. The side reaction product, 2-t-butylpyrimidine, is substantially reduced, especially in the case of the bromo derivative, with catalytic amounts of elemental sulfur