Liu Shi, Xiangqian Liu, H. Zhang
Apr 29, 2011
Citations
1
Influential Citations
59
Citations
Journal
The Journal of organic chemistry
Abstract
Condensation of carbon disulfide with thiols in the presence of K(2)CO(3) generates carbonotrithioate salts in situ, which undergo coupling with 2-iodoanilines and subsequent intramolecular condensation and elimination under assistance of CuBr to afford 2-thio-substituted benzothiazoles. Both aliphatic and aromatic thiols are compatible with this process, delivering the corresponding heterocycles with good diversity.