C. Z. Wang, U. H. Maier, M. Zenk
Mar 2, 2000
Citations
1
Influential Citations
6
Citations
Journal
Journal of natural products
Abstract
3,3',5-Trihydroxybiphenyl-2-carboxylic acid (6), an ester component of the bitter-tasting natural products amarogentin and amaroswerin, was synthesized in six steps in 13.6% overall yield. Its N-acetyl cysteamine thiol ester (9) and its coenzyme A thiol ester (8), a likely biosynthetic precursor of the amarums, were also prepared.