E. Ivleva, A. Kazakova, Y. Klimochkin
Sep 1, 2020
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0
Influential Citations
2
Citations
Journal
Russian Journal of Organic Chemistry
Abstract
A convenient method has been developed for the synthesis of 3,5-bis(hydroxymethyl)adamantan-1-ols via successive nitroxylation of 1,3-bis(acetoxymethyl)adamantanes with fuming nitric acid, alkaline hydrolysis of intermediate 3,5-bis(acetoxymethyl)adamantane-1-yl nitrates, and reaction of the resulting 3,5-bis(hydroxymethyl)adamantan-1-yl nitrates with hydrazine hydrate. 3,5-Bis(hydroxymethyl)adamantan-1-ols have been converted to the corresponding trinitrates by treatment with fuming nitric acids in acetic anhydride.