V. Soloshonok, M. Yasumoto
Jul 1, 2006
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0
Influential Citations
12
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Journal
Journal of Fluorine Chemistry
Abstract
Abstract This paper describes an efficient, practical synthesis of 3,5-bis(trifluoromethyl)benzylamine via biomimetic transamination of 3,5-bis(trifluoromethyl)benzaldehyde with benzylamine. From a synthetic standpoint the reported procedure is highly operationally convenient and scalable as it does not require any chromatographic purification of the intermediate products.