A. Saeed, N. H. Rama, M. Arfan
May 1, 2003
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0
Influential Citations
13
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
3,5-Dimethoxyhomophthalic acid was prepared efficiently in three steps, from 3,5-dimethoxybenzyl bromide via rhodium-catalyzed direct carbonylation to 3,5-dimethoxyphenylacetic acid followed by successive o-formylation and oxidation. Isocoumarins related to agrimonolide and achlisocoumarin 1 were prepared in single step by condensation of the homophthalic acid with appropriate acid chlorides.