W. Mai, S. Green, D. K. Bates
Aug 5, 2010
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Influential Citations
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Journal
Synthetic Communications
Abstract
The synthesis of 3-amino-2,2-dimethyl-8-thia-1-azaspiro[4.5]decane is described. Key steps include the addition of prenyl magnesium bromide to a 4-methoxybenzylimine without reversal of stereochemistry and the iodine-initiated aminocyclization to form the azaspirocycle.