S. David, A. Veyrières
May 1, 1970
Citations
0
Influential Citations
7
Citations
Journal
Carbohydrate Research
Abstract
Abstract Ethyl 2-amino-4,4-diethoxybutyrate (2) was prepared from ethyl malonate. In an alternative route, methyl 2-amino-4,4-dimethoxybutyrate (5) was prepared from dl -aspatic acid. Reduction of 5 with lithium aluminium hydride yielded 3-amino-4-hydroxybutyraldehyde dimethyl acetal (6 from which the N-acetyl derivative 7 and the diethyl dithioacetal 9 could be prepared. Acid hydrolysis of the (S-isome 7′ of compound 7, prepared from l -aspartic acid, yielded the crystalline 3-acetamido-2,3-dideoxy- d -tetrose (10′).