Ligang Liu, Mingzhe Ji, W. Hua
May 1, 2000
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Journal
Journal of Chemical Research
Abstract
1,2-Dimethyl-3,5-diarylpyrazolidine-4-carboxylic acid derivatives 4a–d were synthesised stereo-selectively via intermolecular [3++2] cycloaddition of aldehydes 1a–d and 1,2-dimethylhydrazine dihydrochloride (2) with ethyl trans-cinnamate (3), stereochemistries of which were assigned by 1H-NOESY spectroscopy, and relative configurations confirmed by X-ray diffraction of one of them (4a).