Mariana Useglio, P. Castellano, M. Operto
Oct 1, 2006
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0
Influential Citations
14
Citations
Quality indicators
Journal
Bioorganic & medicinal chemistry letters
Abstract
Six 3H-spiro[benzofuran-2,1'-cyclohexane] derivatives were synthesized from naturally occurring filifolinol, and their classical complement pathway inhibitory activity was determined. IC(50) values of the most potent compounds were comparable to the activity of the natural complement inhibitor K76-COOH and some synthetic tricyclic analogs of it.