Y. Miki*, Y. Aoki, Yasuhiko Tsuzaki
Nov 1, 2005
Citations
0
Influential Citations
10
Citations
Journal
Heterocycles
Abstract
Reaction of 1-benzylindole-2,3-dicarboxylic anhydride with 2,4,6-trimethoxypyridine in the presence of a Lewis acid gave 1-benzyl-3-(2,4,6-trimethoxynicotinoyl)indole-2-carboxylic acid as the sole product in high yield, which could be changed to 1-benzyl-3-(2,4,6-trimethoxynicotinoyl)indole. 1-Benzyl-3-(2,4,6-trimethoxynicotinoyl)indole was converted to 3-methoxy-ellipticine and ellipticine by selective demethylation and triflation of the methoxy group.