G. Jayachitra, R. Anchoori, B. Rao
Oct 20, 2008
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Influential Citations
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Journal
Tetrahedron-asymmetry
Abstract
Abstract A stereoselective approach for the synthesis of (3 R ,4 S )-3-amino-4-methyl pyrrolidine, a part of the structure of a quinoline antibacterial compound and the naphthyridine antitumor agent, is described. The key reaction is the one-pot reduction and regioselective cyclization of azidoditosyl derivative 9 to pyrrolidine 10 .