W. Nawrocka
Feb 3, 2009
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Influential Citations
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Journal
Phosphorus, Sulfur, and Silicon and the Related Elements
Abstract
A series of N- and S-alkylated 4(3H)-quinazolinone derivatives ( 2 – 6 ) have been synthesized by the reaction of 3-amino-2(1H)-thioxo-4(3H)-quinazolinone ( 1 ) with selected chloroformates. 3-Ethoxycarbonylamino-2-ethoxycarbonylthio-4(3H)-quinazolinone ( 3 ) was ammonolysed using ammonia, primary or secondary amines. Depending on the kind of substrates and conditions of ammonolysis, products of various chemical structures were obtained. The products % 2–17 were identified by the results of elemental analysis and by their IR, 1H NMR, and mass spectra.