Li Ming-zhu
2008
Citations
0
Influential Citations
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Citations
Quality indicators
Journal
Journal of Medical Science Yanbian University
Abstract
OBJECTIVE To synthesis the 4-alkyl-1-[2-(pyridin-2-yl ethoxy)ethyl] piperazine and study its effects for ability of memory in mice.METHODSThe compounds(6a~6d) were prepared by using 2-ethylpyridine,through the Whol-Ziegler reaction,and the Williamson reaction.The effects for ability of memory in mice were measured by swimming maze test and darkness avoidance test.RESULTSThe compound 6b has no effects for ability of memory in mice.CONCLUSIONEaster structure is the essential group in ethyl-2(benzyloxy)aryl actecates,which have effects of learning and memory in mice.