Matthew P. Bourbeau, James T. Rider
Jul 20, 2006
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0
Influential Citations
53
Citations
Journal
Organic letters
Abstract
[reaction: see text] A series of 4-alkyl-5-aminoisoxazoles have been synthesized in high yield by nucleophilic addition of lithiated alkyl nitriles to (alpha)-chlorooximes. The scope and limitations of this reaction were examined by varying the nature of the nitrile and chloride oxime.