Yang Guo-jun
2010
Citations
0
Influential Citations
0
Citations
Journal
Journal of Huaiyin Institute of Technology
Abstract
In this paper,4-amino-2-methoxy-5-ethylthio benzoic acid,an intermediate of amisulpride for antipsychotic,was synthesised with 4-amino salicylic acid as raw material after methylation,thiocyanation,hydrolysis and ethylation reactions.The total yield of this route reached 65% with simple operation,easy control and convenient treatment.The target compound was confirmed by IR,HNMR,MS.