G. Jing
2005
Citations
0
Influential Citations
0
Citations
Journal
Journal of Hebei University of Technology
Abstract
4-Chlorobutyl methyl ether is a kind of important intermediate of medicinal substance and organic synthesis.4-chlorobutyl methyl ether was synthesized by tetrahydrofuran,methanol and thionyl chloride.The optimum conditions of reaction were determined as that the mole ratio of tetrahydrofuran to metanol to thionyl chloride is 1: 1.1: 1.6,thionyl chloride drops off at 12 ℃,the reaction temperathure is 120 ℃,and the reaction time is 5 h.