Teng Da-wei
2011
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Journal
Chinese Journal of Pharmaceuticals
Abstract
4-Choloro-2-hydroxyacetophenone was synthesized from 3-aminophenol by acetylation,methylation and Fries rearrangement to give N-(4-acetyl-3-hydroxyphenyl)acetamide,which was subjected to deacetylation and diazotization and Sandmeyer reaction with and overall yield of about 44%.