Shengming Ma, Bin Wu, Zhangjie Shi
Jan 21, 2004
Citations
0
Influential Citations
28
Citations
Journal
The Journal of organic chemistry
Abstract
4-Halo-5-hydroxyfuran-2(5H)-ones were synthesized via the efficient sequential halolactonization-hydroxylation reaction of 4-aryl-2,3-allenoic acids with I(2) or CuX(2) (X = Br or Cl) in moderate to good yields. The structures of the products were established by the X-ray single-crystal diffraction study of 3-methyl-4-iodo-5-phenyl-5-hydroxyl-2(5H)-furanone (2a). A rationale for this reaction was discussed based on some brief mechanistic study.