T. Maruthavanan, P. Venkatesan
Jan 17, 2013
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Influential Citations
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Journal
Natural Product Research
Abstract
A series of 4-hydroxy-3,4-dialkyl-2,6-diaryl-piperidine (7–12) have been synthesised by reduction of 3-alkyl-2,6-diarylpiperidin-4-one using the Grignard reagent. Structural assignments and conformational analysis of the compounds were established based on the spectral studies. All the piperdin-4-ol derivatives (7–12) were assayed for antibacterial, antifungal and anthelmintic activities and they exhibited significant results.