He Deyun
2011
Citations
0
Influential Citations
0
Citations
Journal
Chinese Journal of Pharmaceuticals
Abstract
4-Hydroxyisophthalic acid was synthesized from p-methoxybenzoic acid and paraformaldehyde via Blanc chloromethylation reaction catalyzed by aluminium trichloride and tetrabutyl ammonium bromide to give 3-chloromethyl-4-methoxybenzoic acid,subsequent oxidation and demethylation with an overall yield of about 78%.