J. Wolf, C. M. G. Tanarro, M. Gütschow
2008
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0
Influential Citations
1
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Journal
Helvetica Chimica Acta
Abstract
The synthesis of novel triaryl-substituted 4-(isothiazol-3-yl)morpholines 7 and 8, and 1-(isothiazol-3-yl)piperazines 9–13 by reaction of the corresponding isothiazolium salts 5 and 6 with secondary amines in the presence of t-BuOK in absolute THF is described. Some representatives of the isothiazoles were evaluated as inhibitors of acetylcholinesterase from Electrophorus electricus.