A. Aly, Alan B. Brown, Mohamed Abdel-Aziz
May 1, 2010
Citations
0
Influential Citations
15
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
Reaction of diacyl thiocarbohydrazides with dimethyl but-2-ynedioate in refluxing ethanol led to 4-oxa-thiazolidine-5-ylidene-acetates in good yields. Reaction of the newly prepared N-(2-(propan-2-ylidene)hydrazine-carbonothioyl)arylhydrazides with dimethyl but-2-ynedioate gave the corresponding (Z)-methyl-2-arylhydrazide-4-oxo-3-(propan-2-ylideneamino)thiazolidine-5-ylidene)-acetates. The mechanism is dis-cussed. Antitumor and antioxidant activities have been also investigated.