M. Kihara, M. Kashimoto, Y. Kobayashi
1992
Citations
0
Influential Citations
16
Citations
Journal
Tetrahedron
Abstract
Abstract 4-Substituted 1,2,3,4-tetrahydroisoquinolin-4-ols were prepared from N -(2-iodobenzyl)phenacylamines by an intramolecular Barbier reaction with butyllithium and by an insertion reaction with zerovalent nickel. The scope and limitations of these reactions were discussed.