Johny Wehbe, V. Rolland, A. Fruchier
Mar 8, 2004
Citations
1
Influential Citations
14
Citations
Journal
Tetrahedron-asymmetry
Abstract
Abstract Several new 4-substituted glutamic acid derivatives are described: 4-phosphinomethyl glutamic acid derivatives were prepared starting from (2 S )- N -Boc- tert -butyl-4-methylene glutamate. The 4-carboxymethyl and 4-aminomethyl glutamic acid derivatives were obtained using asymmetric 1,4-addition conjugate of the enolate of Schiff base 1 to unsaturated esters.