Alex H. F. Lee, A. Chan, Tianhu Li
Feb 3, 2003
Citations
0
Influential Citations
23
Citations
Journal
Tetrahedron
Abstract
5-(7-Hydroxyhept-3-enyl)-1,2-dithiolan-3-one 1-oxide 1 possessing both the 1,2-dithiolan-3-one 1-oxide five-membered ring and the double bond at the gamma position of the heterocycle, characteristic of the antibiotic leinamycin, was synthesized. In addition, the activated ester form of 1 was prepared that may be useful for coupling 1 to certain DNA-binding agents.