Meritxell Casadesús, M. Coogan, Li-ling Ooi
Oct 5, 2006
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0
Influential Citations
3
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Journal
Organic & biomolecular chemistry
Abstract
A general synthetic route to 5-alkylidene-1,3-dioxane-4,6-diones, which are a family of axially chiral alkenes, is described. Conformational issues are explored and the platinum-binding properties of these species are discussed. That these alkenes exist as stable enantiomers is established by their partial kinetic resolution upon reaction with cysteine.