T. Benneche, Z. Hussain, A. Scheie
Sep 1, 2008
Citations
0
Influential Citations
29
Citations
Journal
New Journal of Chemistry
Abstract
(E)- and (Z)-5-(Bromomethylene)furan-2(5H)-ones and (E)- and (Z)-3-(bromomethylene)isobenzofuran-1(3H)-ones have been prepared starting from commercially available maleic anhydrides and phthalic anhydrides, respectively. A debrominative decarboxylation or a bromodecarboxylation reaction is a key step in the synthesis. The furanones were investigated for their ability to interfere with microbial communication and biofilm formation by Staphylococcus epidermidis.