Yong Deng, Yi Shen, Yuguo Zhong
Jul 1, 2003
Citations
0
Influential Citations
3
Citations
Journal
Synthetic Communications
Abstract
Abstract The 5-carboxy-1,3-dihydro-1,3-dioxo-2H-isoindole-2-propanoic acid benzyl ester (I), obtained from condensation of 1,3-dihydro-1,3-dioxo-5-isobenzofurancarboxylic acid with β-alanine benzyl ester p-toluenesulfonate, reacted with an appropriate amine (II) to afford the corresponding amide (IIIa–e), which then hydrogenolyzed by 5% palladium-on-carbon to give target compounds (IVa–e).