E. Hoffmann, R. Ikan, A. Galun
Sep 1, 1965
Citations
0
Influential Citations
5
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
5-Fluoroindole was prepared in 4 steps in 46% overall yield from m-fluorotoluene. 7-Methylindole was prepared in 2 steps 2 from 6-dimethylaniline. Both compounds were transformed to the corresponding tryptophanes in high yields. The final hydrolytic step was carried out in aqueous acidic medium.