J. Sośnicki
Sep 1, 2009
Citations
0
Influential Citations
20
Citations
Journal
Synlett
Abstract
Simple and efficient synthesis of 5-functionalised -2-methoxypyridinesfrom 5-bromo-2-methoxypyridine using -[ N-Bu 3 Mg]Li performedin noncryogenic conditions is described. Application of 5-functionalised2-methoxypyridines in the synthesis of 1-substituted 3,6,9,9a-tetrahydroquinolizin-4-onesand 3,5,8,8a-tetrahydro-1 H-quinolin-2-onesvia allylation of the corresponding 5-functionalised N-allyl(or benzyl)pyridin-2-ones using -[allyl N-Bu 2 Mg]Li followedby ring-closing metathesis is presented.