Gitte Van Baelen, G. Lemiére, R. Dommisse
Feb 25, 2009
Citations
1
Influential Citations
12
Citations
Journal
Arkivoc
Abstract
Methyl-5H-pyrrolo(2,3-c)quinoline and 4-methyl-4H-pyrrolo(2,3-c)isoquinoline have been synthesized via a domino condensation - Heck cyclisation of, respectively, 4-bromoquinolin-3- amine or 4-bromoisoquinolin-3-amine and acetaldehyde. Selective methylation of the tricyclic skeletons yielded the title compounds 5-methyl-5H-pyrrolo(2,3-c)quinoline and 4-methyl-4H- pyrrolo(2,3-c)isoquinoline.