Tao Fan, W. Meng, Yu‐Lan Xiao
Nov 22, 2017
Citations
0
Influential Citations
3
Citations
Journal
Tetrahedron Letters
Abstract
Abstract An efficient method for the synthesis of 5-SF 5 substituted indazoles from commercially available 4-nitro-(pentafluorosulfanyl)benzene through vicarious nucleophilic substitution of hydrogen (VNS) reaction, reduction of nitro group and cyclization of resulting anilines were described. Transformations of 5-SF 5 -indazoles led to a variety of SF 5 -substiuted heteroarenes that can serve as a versatile building block for diversity-oriented organic synthesis.