B. Usachev, D. L. Obydennov, V. Sosnovskikh
Aug 1, 2012
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0
Influential Citations
7
Citations
Journal
Russian Chemical Bulletin
Abstract
Abstract6-Tri- and 6-difluoromethylcomanic acids and their ethyl esters reacted with aminoguanidine, predominantly giving 5-RF-pyrazolo[1,5-c]pyrimidines, whereas the reaction of the openchain synthetic equivalents, i.e., ethyl 7,7,7-trifluoro- and 7,7-difluoro-2,4,6-trioxoheptanoates, with this polynucleophile allowed us to obtain regioselectively 2-RF-pyrazolo[1,5-c]pyrimidines.