N. S. Girgis, S. Larson, R. K. Robins
Mar 1, 1989
Citations
0
Influential Citations
24
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
Certain 4-substituted 1H-pyrrolo[2,3-b]pyridines (7-azaindoles) undergo a nucleophilic substitution-rearrangement upon treatment with various primary amines at elevated temperatures to yield N-1-substituted 4-amino-1H-pyrrolo[3,2-c]pyridines (5-azaindoles). Treatment of the same 7-azaindoles with secondary amines under the same reaction conditions led to simple nucleophilic substitution products.