E. Yamato, K. Mashimo, Minoru Hirakura
Sep 25, 1967
Citations
0
Influential Citations
23
Citations
Journal
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
Abstract
Abstract Some sixty 1-substituted 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines were synthesized for pharmacological evaluation. 1-(3′,4′,5′-trimethoxybenzyl) derivative thus prepared was found to be the most active bronchodilator both in vitro and vivo test hitherto described in the literature.