Wu Chun
2004
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Journal
Chinese Journal of Pharmaceuticals
Abstract
Amino-3,4-dihydro-2(1H)-quinolinone was synthesized from aniline and 3-chloropropionylchlorideby condensation and cyclization in presence of AlCl3 to give 3,4-dihydro-2(1H)-quinolinone which subjected to nitrationand reduction with an overall yield of 79%(based on actual reacted aniline).