H. Schirok, C. Alonso‐Alija, M. Michels
Nov 1, 2005
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Influential Citations
16
Citations
Journal
Synthesis
Abstract
A regioselective and highly efficient synthesis of 6-amino-substituted pyridin-2(1H)-ones is presented. In situ generated propiolic acid chloride was used for the cyclization of acyclic β-keto N,S-acetals to afford the heterocyclic core. Substitution by amines led to a flexible access of the target compounds.