Nicolas Leflemme, P. Dallemagne, S. Rault
Dec 17, 2001
Citations
0
Influential Citations
16
Citations
Journal
Tetrahedron Letters
Abstract
Abstract The synthesis of novel 6-arylpiperidine-2,4-diones is described in five steps starting from β-aryl-β-aminoacids via the chain extension of the latter into δ-aryl-δ-amino-β-ketoacids. The chemical pathway involves an acylation of Meldrum's acid and yields useful building blocks for heterocyclic chemistry.