Teng Da-wei
2013
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Journal
Chemistry & Bioengineering
Abstract
6-Iodo-1-tetralone is an important intermediate for the synthesis of 5-HT6 receptor antagonist.It was synthesized from tetrahydronaphthalene,by the reaction of acetylation,oximation of carbonyl,Beckman rearrangement,oxidation and Sandmeyer reaction in five-steps with the total yield of 60%.