A. Singin, T. S. Safonova
Sep 1, 1975
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0
Influential Citations
1
Citations
Journal
Pharmaceutical Chemistry Journal
Abstract
6-Mercaptopurine-8C la (V) was obtained from 4-amino-6-chloro-5-nitropyrimidine (III). 4,5-Diamino-6"mercaptopyrimidine (IV) was synthesized by reacting III with potassium hydrosulfide while continuously passing hydrogen sulfidethrough the mixture. Compound V was obtained by reacting IV with a mixture of formic acid-C 14 and its sodium salt. The yield was 64%, the specific activitywas 21 ~Ci/mg.