F. Reza, Goswami Bhaswati, Kung Pei-Pei
1990
Citations
0
Influential Citations
40
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Trifluoroacetic anhydride at 0° C reacts with a pyridine suspension of deoxyguanosine to generate a polar intermediate, presumably the corresponding 6-pyridyl derivative. The reaction is complete in less than 15 minutes, and is not accompanied by degradation. From this intermediate a variety of 6-substituted deoxyguanosine derivatives can be obtained, some in excellent yields.