T. Goto, S. Utsunomiya, H. Aiba
Jun 1, 1991
Citations
0
Influential Citations
10
Citations
Journal
ChemInform
Abstract
Various 7-substituted 6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-ones are synthesized by the reaction of the corresponding 7-hydroxy derivatives with nucleophiles involving active methylene compounds, aromatics, alcohols, p-toluenethiol, benzenesulfinic acid, triethyl phosphite, ammonia, and amines under acidic or basic conditions. Some synthetic applications of the products obtained are demonstrated to give a 7-methylene derivative and fused tricyclic derivatives.