A. S. Yanni, Z. H. Khalil
Apr 24, 2007
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Journal
Journal of Chemical Technology & Biotechnology
Abstract
Some new 7-alkyl (or aryl) aminomethyl-6-chloroquinoline-5,8-quinones (II) have been obtained through the reaction of 6-chloroquinoline-5,8-quinone with primary aliphatic or aromatic amines and paraformaldehyde in ethanol. On using secondary amines such as piperidine or morpholine in the above reaction, 6-chloro-7-piperidino (or morpholino) methylquinoline-5,8-quinone (III) and (IV) respectively were obtained. The structure of the synthesised compounds was confirmed by elemental analysis and spectral data. The synthesised compounds were also biologically evaluated.